Honoring International Achievement Natural Field R&D Advisor Professor Zhi‑Hong Jiang’s Team Advances to XPRIZE Healthspan Global Final, Exploring New Frontiers in Scientific Anti‑Aging

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Recently, the globally prestigious XPRIZE Healthspan Competition announced its finalist list. Led by Professor Zhi‑Hong Jiang, Vice‑Rector of Macau University of Science and Technology and R&D Advisor of Natural Field, the research team stood out from 602 entries across 58 countries and regions worldwide and secured a spot among the global top 10. As the only Chinese research team advancing to the final round, the team was awarded USD 1 million in special research grants together with access to clinical trial resources, competing for the grand final prize targeted for 2030. This milestone achievement earns high international recognition for China’s research capacity in aging intervention, and delivers powerful scientific momentum for Natural Field’s anti‑aging R&D and product upgrading.

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Initiated by the XPRIZE Foundation and supported by the Hevolution Foundation, XPRIZE Healthspan is a top‑tier global life‑science competition with total prize money exceeding USD 100 million and a seven‑year program cycle. It is committed to advancing practically applicable and scalable aging‑intervention solutions through rigorous human clinical validation. The competition aims to improve muscle function, cognitive performance and immune status in aging populations, bridging cutting‑edge basic research to real‑world public‑health applications. Adopting multi‑layer independent review procedures, the competition strictly evaluates global submissions against four major dimensions: underlying scientific rationale, technical feasibility, scalability potential and clinical‑trial preparedness. Professor Zhi‑Hong Jiang’s RETRO‑EPIGERNA project drew high praise from the jury for its innovative technical strategy. Clinical data demonstrates it can reduce p16/p21 senescence markers by 40%‑60%, showing outstanding efficacy in modulating senescence biomarkers.

A world‑renowned natural‑product chemist, Professor Zhi‑Hong Jiang has devoted decades of research to natural medicines, RNA chemical biology and aging‑mechanism intervention. He serves as Vice‑Rector of Macau University of Science and Technology, Director of the State Key Laboratory of Quality Research in Chinese Medicine, and Director of the MIIT National Center for Molecular Drug Innovation. With postdoctoral experience at Harvard Medical School, he has long promoted translational integration of modernized traditional Chinese medicine, fundamental research and health‑industry development. In anti‑aging research, Professor Zhi‑Hong Jiang’s team focuses on tRNA‑derived small RNAs, NAD+ pathway regulation, and anti‑aging mechanisms of bioactive ingredients derived from Chinese medicinal materials. The research covers senescence biomarkers, mitochondrial function and senescent cell clearance. By combining traditional herbal wisdom with cutting‑edge molecular biology, the team has produced numerous patents and high‑level academic publications, laying solid theoretical and experimental foundations for the anti‑aging industry.

As an in‑depth industry‑university‑research partner, Professor Zhi‑Hong Jiang works as R&D Advisor for Natural Field. He connects leading‑edge academic findings with industrial application requirements, supporting Natural Field to translate state‑of‑the‑art anti‑aging science into market‑ready solution portfolios. Drawing on proprietary NF Co‑Loading® co‑encapsulation liposome delivery technology, Natural Field has developed the NF TriSolve® Anti‑Aging Solution. Moving beyond single‑ingredient development, it adopts a four‑component synergistic compound system integrating liposomal NMN, liposomal CoQ10, ergothioneine and N‑acetylneuraminic acid (sialic acid). Featuring an innovative ginsenoside‑modified liposome framework that replaces conventional cholesterol, the technology addresses common industry pain points including oxidative degradation and poor intestinal absorption of anti‑aging active substances. It enables stable simultaneous encapsulation and synergistic release of both water‑soluble and lipid‑soluble actives. Zebrafish model tests confirm a 97% improvement in anti‑aging efficacy with complete evidence‑based efficacy verification. Natural Field provides standardized and customizable anti‑aging raw materials as well as holistic formulation solutions for functional food and dietary supplement clients.

Breakthroughs in fundamental research are the fountainhead of industrial innovation. The remarkable performance of Professor Zhi‑Hong Jiang’s team in this world‑class anti‑aging contest amplifies the voice of Chinese scientific research on the global life‑science arena. It further confirms that multi‑target synergistic intervention based on evidence‑driven science represents the core development trend for anti‑aging sector. Moving forward, Natural Field will keep deepening industry‑university‑research collaboration with Professor Zhi‑Hong Jiang’s team. Based on the NF Co‑Loading® liposome delivery platform and research progress on molecular aging mechanisms, Natural Field will continue to iterate the NF TriSolve® Anti‑Aging Solution. The company will promote more laboratory‑based research outcomes toward industrial commercialization, empower the broader health industry with robust technologies, and deliver scientifically validated, high‑performance anti‑aging raw materials and product options for global customers.

References: Official news from Macau University of Science and Technology, https://www.must.edu.mo/article/id-13630.html;

XPRIZE Healthspan official announcement, https://go.xprize.org/news/20-healthspan-finalist-teams-advance-in-the-race-to-extend-healthy-aging

References

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